top of page


Acute Effects of Coffee Consumption on Health among Ambulatory Adults
Coffee is one of the most commonly consumed beverages in the world, but the acute health effects of coffee consumption remain uncertain.
Dec 1


Coffee may protect against irregular heartbeats
Drinking caffeinated coffee is safe for people with atrial fibrillation and may help protect against recurrence of the disorder, a new study finds.
Nov 9


Caffeinated Coffee Consumption or Abstinence to Reduce Atrial Fibrillation
In this multicenter randomized clinical trial including 200 patients with persistent AF undergoing cardioversion, the risk of recurrent AF was significantly lower in the group allocated to coffee consumption (47%) compared with the abstinence group (64%).
Nov 9


How Moderate Coffee Drinking Could Transform Your Health
A look at the protective effects of coffee, tea, and caffeine consumption on cardiometabolic health.
Jan 1


Caffeine is linked to Heart Disease Risk in Some: Does it in You?
Caffeine is linked to Heart Disease Risk in Some: Does it in You?
Jan 1


Habitual Coffee, Tea, and Caffeine Consumption, Circulating Metabolites, and the Risk of Cardiometabolic Multimorbidity
Habitual coffee or caffeine intake, especially at a moderate level, was associated with a lower risk of new-onset CM.
Sep 16, 2024


Novel caffeine derivatives mitigate hyperlipidemia by reducing PCSK9 expression and secretion
We have developed novel caffeine derivatives that markedly reduce PCSK9 expression/secretion.
Aug 31, 2024


Systemic Therapeutics at SDDS 2024
Members of Systemic Therapeutics attended the Stanford Drug Discovery Symposium 2024 from April 29 - 30.
May 31, 2024


Association of Coffee Consumption and Prediagnostic Caffeine Metabolites With Incident Parkinson Disease in a Population-Based Cohort
This study demonstrates that the neuroprotection of coffee on PD is attributed to caffeine and its metabolites.
Mar 21, 2024


Characterization of caffeine response regulatory variants in vascular endothelial cells
In hepatocytes, caffeine is known to suppress SREBF2 activity, which reduces PCSK9 expression, and thus increases LDLR expression
Feb 9, 2024
bottom of page
