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Targeting proprotein convertase subtilisin/kexin type 9(PCSK9): from bench to bedside
This ground-breaking research suggested that PCSK9 could degrade CD36
Jan 8, 2024
Roles of Coffee and Its Components in Liver Diseases
coffee components can influence lipid and cancer metabolism by regulating adipogenesis and carcinogenesis
Sep 29, 2023
Current therapeutic targets and multifaceted physiological impacts of caffeine
caffeine has been demonstrated to enhance hepatic ER-linked Ca2+ levels and inhibit the transcriptional activation of SREBP2
Sep 6, 2023
Effect of PCSK9 on atherosclerotic cardiovascular diseases and its mechanisms: Focus on immune regulation
Caffeine inhibits the expression of SREBP2 at the transcriptional level by increasing the Ca2+ concentration in the hepatic ER
Mar 10, 2023
SOPHIE Support for Our Caffeine Project
Systemic Therapeutics investigators have been approved for FedDev funding from the SOPHIE program.
Feb 3, 2023
Drinking tea may lower the risk of diabetes, heart disease and death, mounting research shows
Mounting evidence suggests that drinking several cups of tea per day has numerous health benefits.
Sep 16, 2022
Expanding Biology of PCSK9: Roles in Atherosclerosis and Beyond
To reduce ER stress, Lebeau et al. screened for compounds that enhance ER-entry of Ca2+
Jul 28, 2022
Study: Caffeine Impacts Expression of Genes Known to Mediate Cardiovascular Risk
Evidence suggests that caffeine reduces cardiovascular disease risk.
Feb 18, 2022
McMaster researchers reveal ‘mechanism’ tied to how caffeine could reduce cardiovascular disease
Drinking a few cups of coffee each day can potentially reduce the risk of death from cardiovascular disease.
Feb 10, 2022
Study provides new understanding of caffeine's protective effects on the cardiovascular system
Scientists have a new understanding of the protective effects of caffeine on the cardiovascular system.
Feb 10, 2022
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